Gallery
Overview
The IVM-FS system offers the same functions as the IVM-CMS3 system, with the key difference being its larger stage and modules, designed to accommodate animals larger than mice and rats (older than 6 weeks), such as ferrets, rabbits, and others. With the dark curtain provided, there's no need for a dedicated dark room or specific space just for the microscope.
Specifications
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Laser |
Confocal Laser Unit |
• 405 nm (20mW), 488 nm (20mW), 561 nm (20mW), 640 nm (20mW) |
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Tunable Two-photon Laser Unit |
• Ti: Sapphire laser • Wavelength: 690-1,050 nm, Pulse width < 75 fs, Rep. rate: 80 MHz • Avg. power > 2.5 W, Dispersion compensation: 0 to -43,000 fs² |
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Compact Two-photon Laser Unit |
• Air cooled fs-fiber laser system with built-in power control • Wavelength: 920 nm, Pulse width < 100 fs, Rep. rate: 80 +/-2 MHz • Avg. power > 1.5 W, Dispersion compensation: 0 to -60,000 fs² |
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Fluorescence Detector |
Confocal Detector |
• Wavelength: 400 - 750 nm (DAPI, CFP, GFP, YFP, RFP, Cy5, Cy5.5, etc.) • 4 Ultra-broadband high SNR PMTs (UV to Near IR, Ultra High Sensitivity, Low Dark Current) • Single master pinhole |
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Two-photon Detector |
• Wavelength: 400 - 750 nm (DAPI, CFP, GFP, YFP, RFP, Cy5, Cy5.5, etc.) • 4 high quantum efficiency PMTs (UV to Near IR, Ultra High Sensitivity, Low Dark Current) • Emission Filter: Individual filter can be mounted on each of four detectors. |
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Scan Head |
Scanner |
• Polygonal mirror (Fast axis scanning, Max. 30 kHz) • Galvano scanner (Slow axis scanning, Max. 200 μs/step) |
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Imaging Head |
Objectives |
• Max. 5 objectives are mountable on IVM Engine Software controlled motorized turret (1X-100X) • Compatible for commercial objectives |
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Image |
FOV |
• 100 x 100 μm² - 10 x 10 mm² |
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Pixel Resolution |
• Max. 2,048 x 2,048 pixels |
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Imaging Speed |
• Standard: 30 fps @ 512 x 512 pixels • (Optional) High Speed: 50 fps @ 512 x 512 pixels |
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Animal / Sample Stage |
Movable Stage |
• Travel Range: Manual stage_250 x 80 mm (XY); Automated stage_50 x 50 x 75 mm (XYZ) • Micromanipulation (Max. 0.2 μm resolution) • 3-axis independent control with Jog Dial & IVM Engine Software • Stage maximum load: 10 kg • Distance from plate to objective lens (25 X) = Max. 125 mm |
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Specimen Holder |
• Flexible-design universal in vivo / ex vivo / in vitro specimen holders can be mounted • (Optional) Homeothermic warming system, Holders for window chamber |
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Stage Height Adjustment Module |
• Module designed to raise the plate height for small animals imaging • Mounted between the Manual Z Stage and the Plate Heater |
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Monitoring Camera |
• Real-time live animal / sample monitoring |
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LED Light |
• Installed inside the machine to assist in the observation of live animals or samples |
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Animal Motion Compensation (Tissue stabilization) |
4D In Vivo Imaging Motion Compensation |
• XYZ motion compensation: Averaged image acquisition with motion artifact compensation • Z motion compensation: Image-based sample Z position adjustment for long-term intravital microscopic imaging & sample tracking (Feedback-loop automatic stage control) • T motion compensation: Image-based image XY position adjustment for long-term intravital microscopic imaging & sample tracking (Feedback-loop automatic stage control) • Combination of above three compensation for 4D in vivo motion compensation • Controllable by IVM Engine software |
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Accessories Add-on |
Live Animal Maintenance Unit |
• Body Temp. Monitoring & Feedback Heater Control, including tablet PC • 4CH Rectal Probe, Body Plate Heater, Thermometer Sensor & Cover Glass Heater |
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Inhalation Anesthesia System |
• Whole rodent animal inhalation anesthesia system • Anesthesia mask and connections for longitudinal imaging |
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Antibodies / Dyes |
• Fluorescent labeling agents, vascular dyes and conjugated antibodies |
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Engine & Studio Software |
Image Display |
• Independent 4 single channel display (RGBA channel) • Overlay channel display (Selection among RGBA channel) |
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In Vivo Imaging Modes |
• Mosaic imaging (XY), Z-stack imaging (Z), Time-lapse imaging (T) • Time-lapse imaging at Multi-position (T – M) • Time-lapse & Z-stack imaging (TZ) • Time-lapse & Z-stack imaging at Multi-position (TZ – M) |
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