IF Artificial Skin

The IF Artificial Skin App stratifies skin equivalents into differnet layers including dermis and epidermis and identifies nuclei based on appropriate staining. Further is subclassifies epidermis into stratum corneum, high suprabasal, low suprabasal, basal. The App outputs, area (µm2) of epidemis and dermis, area and mean staining intensity for each sublayer of the epidermis, total number of nuclei for each layer/sublayer and number/% of marker positive cells for each layser and sublayer.

Kremslehner C, Miller A, Nica R, et al. Imaging of metabolic activity adaptations to UV stress, drugs and differentiation at cellular resolution in skin and skin equivalents - Implications for oxidative UV damage. Redox Biol. 2020;37:101583. doi:10.1016/j.redox.2020.101583